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DeCS
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Descriptor English:
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RNA-Induced Silencing Complex
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Descriptor Spanish:
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Complejo Silenciador Inducido por ARN
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Descriptor Portuguese:
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Complexo de Inativação Induzido por RNA
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Synonyms English:
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Complex, RNA-Induced Silencing
Multicomponent Nuclease, RISC
Nuclease, RISC Multicomponent
RISC Multicomponent Nuclease
RNA Induced Silencing Complex
Silencing Complex, RNA-Induced
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Tree Number:
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D08.811.277.352.355.350.810
D08.811.277.352.700.350.810
D12.776.157.725.500.906
D12.776.664.962.500.906
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Definition English:
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A multicomponent, ribonucleoprotein complex comprised of one of the family of ARGONAUTE PROTEINS and the "guide strand" of the one of the 20- to 30-nucleotide small RNAs. RISC cleaves specific RNAs, which are targeted for degradation by homology to these small RNAs. Functions in regulating gene expression are determined by the specific argonaute protein and small RNA including siRNA (RNA, SMALL INTERFERING), miRNA (MICRORNA), or piRNA (PIWI-INTERACTING RNA). |
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See Related English:
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RNA Interference
RNA, Small Interfering
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History Note English:
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2003; use RNA-INDUCED SILENCING COMPLEX (NM) 2001-2002
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Allowable Qualifiers English:
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Record Number:
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37323
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Unique Identifier:
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D034743
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Occurrence in VHL:
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Similar:
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DeCS
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